A Phase II Dose-Ranging Study Evaluating the Efficacy and Safety of the Orexin Receptor Antagonist Filorexant (MK-6096) in Patients with Primary Insomnia

BACKGROUND: Filorexant (MK-6096) is an orexin receptor antagonist; here, we evaluate the efficacy of filorexant in the treatment of insomnia in adults. METHODS: A double-blind, placebo-controlled, randomized, two 4-week–period, adaptive crossover polysomnography study was conducted at 51 sites world...

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Detalles Bibliográficos
Autores principales: Connor, Kathryn M., Mahoney, Erin, Jackson, Saheeda, Hutzelmann, Jill, Zhao, Xin, Jia, Nan, Snyder, Ellen, Snavely, Duane, Michelson, David, Roth, Thomas, Herring, W. Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006195/
https://www.ncbi.nlm.nih.gov/pubmed/26979830
http://dx.doi.org/10.1093/ijnp/pyw022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006195/
https://www.ncbi.nlm.nih.gov/pubmed/26979830
http://dx.doi.org/10.1093/ijnp/pyw022

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