Valproic Acid and Other HDAC Inhibitors Upregulate FGF21 Gene Expression and Promote Process Elongation in Glia by Inhibiting HDAC2 and 3

BACKGROUND: Fibroblast growth factor 21, a novel regulator of glucose and lipid metabolism, has robust protective properties in neurons. However, its expression and function in glia are unknown. Valproic acid, a mood stabilizer and anticonvulsant, is a histone deacetylase inhibitor and a dynamic gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Leng, Yan, Wang, Junyu, Wang, Zhifei, Liao, Hsiao-Mei, Wei, Monica, Leeds, Peter, Chuang, De-Maw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006201/
https://www.ncbi.nlm.nih.gov/pubmed/27207921
http://dx.doi.org/10.1093/ijnp/pyw035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006201/
https://www.ncbi.nlm.nih.gov/pubmed/27207921
http://dx.doi.org/10.1093/ijnp/pyw035

Ejemplares similares