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Time-varying SMART design and data analysis methods for evaluating adaptive intervention effects
BACKGROUND: In a standard two-stage SMART design, the intermediate response to the first-stage intervention is measured at a fixed time point for all participants. Subsequently, responders and non-responders are re-randomized and the final outcome of interest is measured at the end of the study. To...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006275/ https://www.ncbi.nlm.nih.gov/pubmed/27578254 http://dx.doi.org/10.1186/s12874-016-0202-7 |