Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease mechanism

BACKGROUND: Genome-wide association studies provide important insights to the genetic component of disease risks. However, an existing challenge is how to incorporate collective effects of interactions beyond the level of independent single nucleotide polymorphism (SNP) tests. While methods consider...

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Detalles Bibliográficos
Autores principales: Woo, Hyung Jun, Yu, Chenggang, Kumar, Kamal, Gold, Bert, Reifman, Jaques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006276/
https://www.ncbi.nlm.nih.gov/pubmed/27576376
http://dx.doi.org/10.1186/s12864-016-2871-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006276/
https://www.ncbi.nlm.nih.gov/pubmed/27576376
http://dx.doi.org/10.1186/s12864-016-2871-3

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