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Biochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif

BACKGROUND: The motif ACTAYRNNNCCCR (Y being C or T, R being A or G, and N any nucleotide), called M4, was discovered as a putative cis-regulatory element, present 520 times in human promoter regions. Of these, 317 (61 %) are conserved within promoter sequences of four related organisms: human, mous...

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Detalles Bibliográficos
Autores principales: Trung, Ngo Tat, Kremmer, Elisabeth, Mittler, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006282/
https://www.ncbi.nlm.nih.gov/pubmed/27576892
http://dx.doi.org/10.1186/s12864-016-3033-3