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Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders

BACKGROUND: Type II DNA topoisomerases (TOP2) regulate DNA topology by generating transient double stranded breaks during replication and transcription. Topoisomerase II beta (TOP2B) facilitates rapid gene expression and functions at the later stages of development and differentiation. To gain new i...

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Detalles Bibliográficos
Autores principales: Uusküla-Reimand, Liis, Hou, Huayun, Samavarchi-Tehrani, Payman, Rudan, Matteo Vietri, Liang, Minggao, Medina-Rivera, Alejandra, Mohammed, Hisham, Schmidt, Dominic, Schwalie, Petra, Young, Edwin J., Reimand, Jüri, Hadjur, Suzana, Gingras, Anne-Claude, Wilson, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006368/
https://www.ncbi.nlm.nih.gov/pubmed/27582050
http://dx.doi.org/10.1186/s13059-016-1043-8