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Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders
BACKGROUND: Type II DNA topoisomerases (TOP2) regulate DNA topology by generating transient double stranded breaks during replication and transcription. Topoisomerase II beta (TOP2B) facilitates rapid gene expression and functions at the later stages of development and differentiation. To gain new i...
Autores principales: | Uusküla-Reimand, Liis, Hou, Huayun, Samavarchi-Tehrani, Payman, Rudan, Matteo Vietri, Liang, Minggao, Medina-Rivera, Alejandra, Mohammed, Hisham, Schmidt, Dominic, Schwalie, Petra, Young, Edwin J., Reimand, Jüri, Hadjur, Suzana, Gingras, Anne-Claude, Wilson, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006368/ https://www.ncbi.nlm.nih.gov/pubmed/27582050 http://dx.doi.org/10.1186/s13059-016-1043-8 |
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