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Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits

BACKGROUND: Primary central nervous system (CNS) neoplasms and brain metastases are routinely treated with whole-brain radiation. Long-term survival occurs in many patients, but their quality of life is severely affected by the development of cognitive deficits, and there is no treatment to prevent...

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Detalles Bibliográficos
Autores principales: Feng, Xi, Jopson, Timothy D., Paladini, Maria Serena, Liu, Sharon, West, Brian L., Gupta, Nalin, Rosi, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006433/
https://www.ncbi.nlm.nih.gov/pubmed/27576527
http://dx.doi.org/10.1186/s12974-016-0671-y