Astroglia acquires a toxic neuroinflammatory role in response to the cerebrospinal fluid from amyotrophic lateral sclerosis patients

BACKGROUND: Non-cell autonomous toxicity is one of the potential mechanisms implicated in the etiopathogenesis of amyotrophic lateral sclerosis (ALS). However, the exact role of glial cells in ALS pathology is yet to be fully understood. In a cellular model recapitulating the pathology of sporadic A...

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Detalles Bibliográficos
Autores principales: Mishra, Pooja-Shree, Dhull, Dinesh K., Nalini, A., Vijayalakshmi, K., Sathyaprabha, T. N., Alladi, Phalguni Anand, Raju, Trichur R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006495/
https://www.ncbi.nlm.nih.gov/pubmed/27578023
http://dx.doi.org/10.1186/s12974-016-0698-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006495/
https://www.ncbi.nlm.nih.gov/pubmed/27578023
http://dx.doi.org/10.1186/s12974-016-0698-0

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