New tools to convert bacterial artificial chromosomes to a self-excising design and their application to a herpes simplex virus type 1 infectious clone

BACKGROUND: Infectious clones are fundamental tools for the study of many viruses, allowing for efficient mutagenesis and reproducible production of genetically-defined strains. For the large dsDNA genomes of the herpesviridae, bacterial artificial chromosomes have become the cloning vector of choic...

Descripción completa

Detalles Bibliográficos
Autores principales: Richards, Alexsia L., Sollars, Patricia J., Smith, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006514/
https://www.ncbi.nlm.nih.gov/pubmed/27580861
http://dx.doi.org/10.1186/s12896-016-0295-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006514/
https://www.ncbi.nlm.nih.gov/pubmed/27580861
http://dx.doi.org/10.1186/s12896-016-0295-4

Ejemplares similares