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Secreted herpes simplex virus-2 glycoprotein G alters thermal pain sensitivity by modifying NGF effects on TRPV1

Genital herpes is a painful disease frequently caused by the neurotropic pathogen herpes simplex virus type 2 (HSV-2). We have recently shown that HSV-2-secreted glycoprotein G (SgG2) interacts with and modulates the activity of the neurotrophin nerve growth factor (NGF). This interaction modifies t...

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Detalles Bibliográficos
Autores principales: Cabrera, Jorge Rubén, Viejo-Borbolla, Abel, Alcamí, Antonio, Wandosell, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006520/
https://www.ncbi.nlm.nih.gov/pubmed/27576911
http://dx.doi.org/10.1186/s12974-016-0677-5