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Decreased expression of stomatin predicts poor prognosis in HER2-positive breast cancer

BACKGROUND: Human epidermal growth factor receptor-2 (HER2) is a transmembrane tyrosine kinase receptor that is overexpressed in 25 to 30 % of human breast cancers and is preferentially localized in lipid rafts. Stomatin is a membrane protein that is absent from the erythrocyte plasma membrane in pa...

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Detalles Bibliográficos
Autores principales: Chen, Chin-Yau, Yang, Chih-Yung, Chen, Yen-Chung, Shih, Chia-Wen, Lo, Su-Shun, Lin, Chi-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006529/
https://www.ncbi.nlm.nih.gov/pubmed/27577936
http://dx.doi.org/10.1186/s12885-016-2681-7