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Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells

BACKGROUND: In breast cancer, the epithelial to mesenchyme transition (EMT) is associated to tumour dissemination, drug resistance and high relapse risks. It is partly controlled by epigenetic modifications such as histone acetylation and methylation. The identification of genes involved in these re...

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Detalles Bibliográficos
Autores principales: Gregoire, Jean-Marc, Fleury, Laurence, Salazar-Cardozo, Clara, Alby, Frédéric, Masson, Véronique, Arimondo, Paola Barbara, Ausseil, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006536/
https://www.ncbi.nlm.nih.gov/pubmed/27581651
http://dx.doi.org/10.1186/s12885-016-2683-5