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Methylation pattern analysis in prostate cancer tissue: identification of biomarkers using an MS-MLPA approach
BACKGROUND: Epigenetic silencing mediated by CpG island methylation is a common feature of many cancers. Characterizing aberrant DNA methylation changes associated with prostate carcinogenesis could potentially identify a tumour-specific methylation pattern, facilitating the early diagnosis of prost...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006561/ https://www.ncbi.nlm.nih.gov/pubmed/27576364 http://dx.doi.org/10.1186/s12967-016-1014-6 |