Monoclonal antibodies against DNA-binding tips of DNABII proteins disrupt biofilms in vitro and induce bacterial clearance in vivo

The vast majority of chronic and recurrent bacterial diseases are attributed to the presence of a recalcitrant biofilm that contributes significantly to pathogenesis. As such, these diseases will require an innovative therapeutic approach. We targeted DNABII proteins, an integral component of extrac...

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Detalles Bibliográficos
Autores principales: Novotny, Laura A., Jurcisek, Joseph A., Goodman, Steven D., Bakaletz, Lauren O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006588/
https://www.ncbi.nlm.nih.gov/pubmed/27342872
http://dx.doi.org/10.1016/j.ebiom.2016.06.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006588/
https://www.ncbi.nlm.nih.gov/pubmed/27342872
http://dx.doi.org/10.1016/j.ebiom.2016.06.022

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