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A Novel Peptide Thrombopoietin Mimetic Designing and Optimization Using Computational Approach

Thrombopoietin receptor (TPOR) is a cytokine receptor protein present on the cell surface. The activation of TPOR by thrombopoietin (TPO) (a glycoprotein hormone) triggers an intracellular cascade of megakaryocytopoiesis for the formation of platelets. Recent studies on ex vivo megakaryocytopoiesis...

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Detalles Bibliográficos
Autores principales: Singh, Vimal Kishor, Kumar, Neeraj, Kalsan, Manisha, Saini, Abhishek, Chandra, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006622/
https://www.ncbi.nlm.nih.gov/pubmed/27630985
http://dx.doi.org/10.3389/fbioe.2016.00069