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Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies

Current screening methods for ovarian cancer can only detect advanced disease. Earlier detection has proved difficult because the molecular precursors involved in the natural history of the disease are unknown. To identify early driver mutations in ovarian cancer cells, we used dense whole genome se...

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Detalles Bibliográficos
Autores principales: Hellner, Karin, Miranda, Fabrizio, Fotso Chedom, Donatien, Herrero-Gonzalez, Sandra, Hayden, Daniel M., Tearle, Rick, Artibani, Mara, KaramiNejadRanjbar, Mohammad, Williams, Ruth, Gaitskell, Kezia, Elorbany, Samar, Xu, Ruoyan, Laios, Alex, Buiga, Petronela, Ahmed, Karim, Dhar, Sunanda, Zhang, Rebecca Yu, Campo, Leticia, Myers, Kevin A., Lozano, María, Ruiz-Miró, María, Gatius, Sónia, Mota, Alba, Moreno-Bueno, Gema, Matias-Guiu, Xavier, Benítez, Javier, Witty, Lorna, McVean, Gil, Leedham, Simon, Tomlinson, Ian, Drmanac, Radoje, Cazier, Jean-Baptiste, Klein, Robert, Dunne, Kevin, Bast, Robert C., Kennedy, Stephen H., Hassan, Bassim, Lise, Stefano, Garcia, María José, Peters, Brock A., Yau, Christopher, Sauka-Spengler, Tatjana, Ahmed, Ahmed Ashour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006641/
https://www.ncbi.nlm.nih.gov/pubmed/27492892
http://dx.doi.org/10.1016/j.ebiom.2016.06.048