Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry

Tyrosine sulfation is a post-translational modification that facilitates protein-protein interaction. Two sulfated tyrosines (Tys173 and Tys177) were recently identified within the second variable (V2) loop of the major HIV-1 envelope glycoprotein, gp120, and shown to contribute to stabilizing the i...

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Detalles Bibliográficos
Autores principales: Cimbro, Raffaello, Peterson, Francis C., Liu, Qingbo, Guzzo, Christina, Zhang, Peng, Miao, Huiyi, Van Ryk, Donald, Ambroggio, Xavier, Hurt, Darrell E., De Gioia, Luca, Volkman, Brian F., Dolan, Michael A., Lusso, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006643/
https://www.ncbi.nlm.nih.gov/pubmed/27389109
http://dx.doi.org/10.1016/j.ebiom.2016.06.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006643/
https://www.ncbi.nlm.nih.gov/pubmed/27389109
http://dx.doi.org/10.1016/j.ebiom.2016.06.037

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