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β(2)-Glycoprotein I Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis by Suppressing the Phosphorylation of Extracellular Signal-Regulated Kinase 1/2, Akt, and Endothelial Nitric Oxide Synthase

Angiogenesis is the process of new blood vessel formation, and it plays a key role in various physiological and pathological conditions. The β(2)-glycoprotein I (β(2)-GPI) is a plasma glycoprotein with multiple biological functions, some of which remain to be elucidated. This study aimed to identify...

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Detalles Bibliográficos
Autores principales: Chiu, Wen-Chin, Chiou, Tzeon-Jye, Chung, Meng-Ju, Chiang, An-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006999/
https://www.ncbi.nlm.nih.gov/pubmed/27579889
http://dx.doi.org/10.1371/journal.pone.0161950