Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent

Gli2 is the primary transcriptional activator of Hedgehog signalling in mammals. Upon stimulation of the pathway, Gli2 moves into the cilium before reaching the nucleus. However, the mechanisms underlying its entry into the cilium are not completely understood. Since several similarities have been r...

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Detalles Bibliográficos
Autores principales: Torrado, Belén, Graña, Martín, Badano, José L., Irigoín, Florencia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007031/
https://www.ncbi.nlm.nih.gov/pubmed/27579771
http://dx.doi.org/10.1371/journal.pone.0162033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007031/
https://www.ncbi.nlm.nih.gov/pubmed/27579771
http://dx.doi.org/10.1371/journal.pone.0162033

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