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Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses

Emerging data support a role for antibody Fc-mediated antiviral activity in vaccine efficacy and in the control of HIV-1 replication by broadly neutralizing antibodies. Antibody-mediated virus internalization is an Fc-mediated function that may act at the portal of entry whereby effector cells may b...

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Detalles Bibliográficos
Autores principales: Tay, Matthew Zirui, Liu, Pinghuang, Williams, LaTonya D., McRaven, Michael D, Sawant, Sheetal, Gurley, Thaddeus C, Xu, Thomas T., Dennison, S. Moses, Liao, Hua-Xin, Chenine, Agnès-Laurence, Alam, S. Munir, Moody, M. Anthony, Hope, Thomas J., Haynes, Barton F., Tomaras, Georgia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007037/
https://www.ncbi.nlm.nih.gov/pubmed/27579713
http://dx.doi.org/10.1371/journal.ppat.1005817