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A Qualitative Model of the Differentiation Network in Chondrocyte Maturation: A Holistic View of Chondrocyte Hypertrophy

Differentiation of chondrocytes towards hypertrophy is a natural process whose control is essential in endochondral bone formation. It is additionally thought to play a role in several pathophysiological processes, with osteoarthritis being a prominent example. We perform a dynamic analysis of a qua...

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Detalles Bibliográficos
Autores principales: Kerkhofs, Johan, Leijten, Jeroen, Bolander, Johanna, Luyten, Frank P., Post, Janine N., Geris, Liesbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007039/
https://www.ncbi.nlm.nih.gov/pubmed/27579819
http://dx.doi.org/10.1371/journal.pone.0162052