Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent “Pimonidazole” in Hypoxia

Hypoxia, or low oxygen concentration, is a key factor promoting tumor progression and angiogenesis and resistance of cancer to radiotherapy and chemotherapy. 2-Nitroimidazole-based agents have been widely used in pathological and nuclear medicine examinations to detect hypoxic regions in tumors; in...

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Detalles Bibliográficos
Autores principales: Masaki, Yukiko, Shimizu, Yoichi, Yoshioka, Takeshi, Feng, Fei, Zhao, Songji, Higashino, Kenichi, Numata, Yoshito, Kuge, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007049/
https://www.ncbi.nlm.nih.gov/pubmed/27580239
http://dx.doi.org/10.1371/journal.pone.0161639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007049/
https://www.ncbi.nlm.nih.gov/pubmed/27580239
http://dx.doi.org/10.1371/journal.pone.0161639

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