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Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system

Ribosome assembly is an essential process that consumes prodigious quantities of cellular resources. Ribosomal proteins cannot be overproduced in Saccharomyces cerevisiae because the excess proteins are rapidly degraded. However, the responsible quality control (QC) mechanisms remain poorly characte...

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Detalles Bibliográficos
Autores principales: Sung, Min-Kyung, Reitsma, Justin M., Sweredoski, Michael J., Hess, Sonja, Deshaies, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007085/
https://www.ncbi.nlm.nih.gov/pubmed/27385339
http://dx.doi.org/10.1091/mbc.E16-05-0290