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Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution
The normal distribution of nuclear envelope transmembrane proteins (NETs) is disrupted in several human diseases. NETs are synthesized on the endoplasmic reticulum and then transported from the outer nuclear membrane (ONM) to the inner nuclear membrane (INM). Quantitative determination of the distri...
Autores principales: | Mudumbi, Krishna C, Schirmer, Eric C, Yang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007294/ https://www.ncbi.nlm.nih.gov/pubmed/27558844 http://dx.doi.org/10.1038/ncomms12562 |
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