YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

Methylation at the N6 position of adenosine (m(6)A) is the most abundant RNA modification within protein-coding and long noncoding RNAs in eukaryotes and is a reversible process with important biological functions. YT521-B homology domain family (YTHDF) proteins are the readers of m(6)A, the binding...

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Detalles Bibliográficos
Autores principales: Du, Hao, Zhao, Ya, He, Jinqiu, Zhang, Yao, Xi, Hairui, Liu, Mofang, Ma, Jinbiao, Wu, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007331/
https://www.ncbi.nlm.nih.gov/pubmed/27558897
http://dx.doi.org/10.1038/ncomms12626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007331/
https://www.ncbi.nlm.nih.gov/pubmed/27558897
http://dx.doi.org/10.1038/ncomms12626

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