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Prophylactic Chronic Zinc Administration Increases Neuroinflammation in a Hypoxia-Ischemia Model

Acute and subacute administration of zinc exert neuroprotective effects in hypoxia-ischemia animal models; yet the effect of chronic administration of zinc still remains unknown. We addressed this issue by injecting zinc at a tolerable dose (0.5 mg/kg weight, i.p.) for 14 days before common carotid...

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Detalles Bibliográficos
Autores principales: Tomas-Sanchez, Constantino, Blanco-Alvarez, Victor Manuel, Gonzalez-Barrios, Juan Antonio, Martinez-Fong, Daniel, Garcia-Robles, Guadalupe, Soto-Rodriguez, Guadalupe, Brambila, Eduardo, Torres-Soto, Maricela, Gonzalez-Vazquez, Alejandro, Aguilar-Peralta, Ana Karina, Garate-Morales, José-Luis, Aguilar-Carrasco, Luis-Angel, Limón, Daniel I., Cebada, Jorge, Leon-Chavez, Bertha Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007350/
https://www.ncbi.nlm.nih.gov/pubmed/27635404
http://dx.doi.org/10.1155/2016/4039837