Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5

Whether transcriptional regulators are functionally involved in mitosis is a fundamental question in cell biology. Here we report that the RNF20/40 complex, a major ubiquitin ligase catalysing histone H2B monoubiquitination, interacts with the motor protein Eg5 during mitosis and participates in spi...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Yang, Huo, Dawei, Gao, Jie, Wu, Heng, Ye, Zheng, Liu, Zhe, Zhang, Kai, Shan, Lin, Zhou, Xing, Wang, Yue, Su, Dongxue, Ding, Xiang, Shi, Lei, Wang, Yan, Shang, Yongfeng, Xuan, Chenghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007379/
https://www.ncbi.nlm.nih.gov/pubmed/27557628
http://dx.doi.org/10.1038/ncomms12648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007379/
https://www.ncbi.nlm.nih.gov/pubmed/27557628
http://dx.doi.org/10.1038/ncomms12648

Ejemplares similares