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Molecular logic of the Zur-regulated zinc deprivation response in Bacillus subtilis

Bacteria respond dynamically to the changes in zinc availability. Repression by the Bacillus subtilis transcription factor Zur requires Zn(II), which binds with negative cooperativity to two regulatory sites per dimer to form, sequentially, Zur(2):Zn(3) and Zur(2):Zn(4) forms of the repressor. Here...

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Detalles Bibliográficos
Autores principales: Shin, Jung-Ho, Helmann, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007448/
https://www.ncbi.nlm.nih.gov/pubmed/27561249
http://dx.doi.org/10.1038/ncomms12612