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Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins

Human defensins are innate immune defense peptides with a remarkably broad repertoire of anti-pathogen activities. In addition to modulating immune response, inflammation, and angiogenesis, disintegrating bacterial membranes, and inactivating bacterial toxins, defensins are known to intercept variou...

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Detalles Bibliográficos
Autores principales: Kudryashova, Elena, Koneru, Pratibha C., Kvaratskhelia, Mamuka, Strömstedt, Adam A., Lu, Wuyuan, Kudryashov, Dmitri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007486/
https://www.ncbi.nlm.nih.gov/pubmed/27581352
http://dx.doi.org/10.1038/srep32499