Cargando…

The Na(+)/Ca(2+), K(+) exchanger 2 modulates mammalian cone phototransduction

Calcium ions (Ca(2+)) modulate the phototransduction cascade of vertebrate cone photoreceptors to tune gain, inactivation, and light adaptation. In darkness, the continuous current entering the cone outer segment through cGMP-gated (CNG) channels is carried in part by Ca(2+), which is then extruded...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakurai, Keisuke, Vinberg, Frans, Wang, Tian, Chen, Jeannie, Kefalov, Vladimir J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007492/
https://www.ncbi.nlm.nih.gov/pubmed/27580676
http://dx.doi.org/10.1038/srep32521