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ge-CRISPR - An integrated pipeline for the prediction and analysis of sgRNAs genome editing efficiency for CRISPR/Cas system

Genome editing by sgRNA a component of CRISPR/Cas system emerged as a preferred technology for genome editing in recent years. However, activity and stability of sgRNA in genome targeting is greatly influenced by its sequence features. In this endeavor, a few prediction tools have been developed to...

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Detalles Bibliográficos
Autores principales: Kaur, Karambir, Gupta, Amit Kumar, Rajput, Akanksha, Kumar, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007494/
https://www.ncbi.nlm.nih.gov/pubmed/27581337
http://dx.doi.org/10.1038/srep30870