Inhibition of caspase-9 aggravates acute liver injury through suppression of cytoprotective autophagy

Acute liver disease is characterized by inflammation, oxidative stress and necrosis, which can greatly influence the long term clinical outcome and lead to liver failure or cancer. Here, we initially demonstrated the beneficial role of caspase-9-dependent autophagy in acute liver injury. Treatment w...

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Detalles Bibliográficos
Autores principales: Guo, Rui, Lin, Bin, Pan, Jing Fei, Liong, Emily C., Xu, Ai Min, Youdim, Moussa, Fung, Man Lung, So, Kwok Fai, Tipoe, George L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007529/
https://www.ncbi.nlm.nih.gov/pubmed/27580936
http://dx.doi.org/10.1038/srep32447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007529/
https://www.ncbi.nlm.nih.gov/pubmed/27580936
http://dx.doi.org/10.1038/srep32447

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