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In silico identification of enhancers on the basis of a combination of transcription factor binding motif occurrences

Enhancers interact with gene promoters and form chromatin looping structures that serve important functions in various biological processes, such as the regulation of gene transcription and cell differentiation. However, enhancers are difficult to identify because they generally do not have fixed po...

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Detalles Bibliográficos
Autores principales: Fang, Yaping, Wang, Yunlong, Zhu, Qin, Wang, Jia, Li, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007594/
https://www.ncbi.nlm.nih.gov/pubmed/27582178
http://dx.doi.org/10.1038/srep32476