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The p90 ribosomal S6 kinase 2 specifically affects mitotic progression by regulating the basal level, distribution and stability of mitotic spindles

RSK2, also known as RPS6KA3 (ribosomal protein S6 kinase, 90 kDa, polypeptide 3), is a downstream kinase of the mitogen-activated protein kinase (MAPK) pathway, which is important in regulating survival, transcription, growth and proliferation. However, its biological role in mitotic progression is...

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Detalles Bibliográficos
Autores principales: Park, Yun Yeon, Nam, Hyun-Ja, Do, Mihyang, Lee, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007638/
https://www.ncbi.nlm.nih.gov/pubmed/27491410
http://dx.doi.org/10.1038/emm.2016.61