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Visualization of in vivo metabolic flows reveals accelerated utilization of glucose and lactate in penumbra of ischemic heart

Acute ischemia produces dynamic changes in labile metabolites. To capture snapshots of such acute metabolic changes, we utilized focused microwave treatment to fix metabolic flow in vivo in hearts of mice 10 min after ligation of the left anterior descending artery. The left ventricle was subdivided...

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Detalles Bibliográficos
Autores principales: Sugiura, Yuki, Katsumata, Yoshinori, Sano, Motoaki, Honda, Kurara, Kajimura, Mayumi, Fukuda, Keiichi, Suematsu, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007669/
https://www.ncbi.nlm.nih.gov/pubmed/27581923
http://dx.doi.org/10.1038/srep32361