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Visualization of in vivo metabolic flows reveals accelerated utilization of glucose and lactate in penumbra of ischemic heart
Acute ischemia produces dynamic changes in labile metabolites. To capture snapshots of such acute metabolic changes, we utilized focused microwave treatment to fix metabolic flow in vivo in hearts of mice 10 min after ligation of the left anterior descending artery. The left ventricle was subdivided...
Autores principales: | Sugiura, Yuki, Katsumata, Yoshinori, Sano, Motoaki, Honda, Kurara, Kajimura, Mayumi, Fukuda, Keiichi, Suematsu, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007669/ https://www.ncbi.nlm.nih.gov/pubmed/27581923 http://dx.doi.org/10.1038/srep32361 |
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