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Transcriptomic analysis reveals sex-specific differences in the expression of Dcl1 and Fis1 genes in the radio-adaptive response of thymocytes to TRP53-mediated apoptosis

BACKGROUND: Radio-Adaptive Response (RAR) is a biological defense mechanism whereby exposure to low dose ionizing radiation (IR) mitigates the detrimental effects of high dose irradiation. RAR has been widely observed in vivo using as endpoint less induction of apoptosis. However, sex differences as...

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Detalles Bibliográficos
Autores principales: López-Nieva, Pilar, Malavé, Manuel, González-Sánchez, Laura, Fernández-Piqueras, José, Fernández-Navarro, Pablo, Santos, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007679/
https://www.ncbi.nlm.nih.gov/pubmed/27581076
http://dx.doi.org/10.1186/s12864-016-3036-0