Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis

BACKGROUND: Wnt11 is a member of the Wnt family of secreted signals controlling the early steps in ureteric bud (UB) branching. Due to the reported lethality of Wnt11 knockout embryos in utero, its role in later mammalian kidney organogenesis remains open. The presence of Wnt11 in the emerging tubul...

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Detalles Bibliográficos
Autores principales: Nagy, Irina I., Xu, Qi, Naillat, Florence, Ali, Nsrein, Miinalainen, Ilkka, Samoylenko, Anatoly, Vainio, Seppo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007805/
https://www.ncbi.nlm.nih.gov/pubmed/27582005
http://dx.doi.org/10.1186/s12861-016-0131-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007805/
https://www.ncbi.nlm.nih.gov/pubmed/27582005
http://dx.doi.org/10.1186/s12861-016-0131-z

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