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Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon chain length

BACKGROUND: Aldehyde-deformylating oxygenase (ADO) is an important enzyme involved in the biosynthetic pathway of fatty alk(a/e)nes in cyanobacteria. However, ADO exhibits quite low chain-length specificity with respect to the substrates ranging from C(4) to C(18) aldehydes, which is not suitable fo...

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Detalles Bibliográficos
Autores principales: Bao, Luyao, Li, Jian-Jun, Jia, Chenjun, Li, Mei, Lu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007808/
https://www.ncbi.nlm.nih.gov/pubmed/27588038
http://dx.doi.org/10.1186/s13068-016-0596-9