Loss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth

Stimulating tumor cell senescence and apoptosis are proven methods for therapeutically combating cancer. However, senescence and apoptosis are conventionally viewed as parallel, not sequential, processes. We have discovered that the metastasis-promoting phosphatase, PRL-3, is transcriptionally regul...

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Detalles Bibliográficos
Autores principales: Gari, H H, DeGala, G D, Lucia, M S, Lambert, J R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007826/
https://www.ncbi.nlm.nih.gov/pubmed/27526109
http://dx.doi.org/10.1038/oncsis.2016.50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007826/
https://www.ncbi.nlm.nih.gov/pubmed/27526109
http://dx.doi.org/10.1038/oncsis.2016.50

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