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Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization

Exosomes are responsible for intercellular communication between tumor cells and others in the tumor microenvironment. These microvesicles promote oncogensis and can support towards metastasis by promoting a pro-tumorogenic environment. Modifying the exosomal content and exosome delivery are emergin...

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Detalles Bibliográficos
Autores principales: Trivedi, M, Talekar, M, Shah, P, Ouyang, Q, Amiji, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007827/
https://www.ncbi.nlm.nih.gov/pubmed/27500388
http://dx.doi.org/10.1038/oncsis.2016.52