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FLASH protects ZEB1 from degradation and supports cancer cells' epithelial-to-mesenchymal transition

Cancer metastasis remains a significant challenge and the leading cause of cancer-associated deaths. It is postulated that during metastasis cells undergo epithelial-to-mesenchymal transition (EMT), a process characterized by loss of cell–cell contacts and increased migratory and invasive potential....

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Detalles Bibliográficos
Autores principales: Abshire, C F, Carroll, J L, Dragoi, A-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007829/
https://www.ncbi.nlm.nih.gov/pubmed/27526108
http://dx.doi.org/10.1038/oncsis.2016.55