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FLASH protects ZEB1 from degradation and supports cancer cells' epithelial-to-mesenchymal transition
Cancer metastasis remains a significant challenge and the leading cause of cancer-associated deaths. It is postulated that during metastasis cells undergo epithelial-to-mesenchymal transition (EMT), a process characterized by loss of cell–cell contacts and increased migratory and invasive potential....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007829/ https://www.ncbi.nlm.nih.gov/pubmed/27526108 http://dx.doi.org/10.1038/oncsis.2016.55 |