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Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance

BACKGROUND/OBJECTIVES: Limited numbers of studies demonstrated obesity-induced macrophage infiltration in skeletal muscle (SM), but dynamics of immune cell accumulation and contribution of T cells to SM insulin resistance are understudied. SUBJECTS/METHODS: T cells and macrophage markers were examin...

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Detalles Bibliográficos
Autores principales: Khan, Ilvira M., Dai Perrard, Xiao-Yuan, Brunner, Gerd, Lui, Hua, Sparks, Lauren M., Smith, Steven R., Wang, Xukui, Shi, Zheng-Zheng, Lewis, Dorothy E., Wu, Huaizhu, Ballantyne, Christie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007876/
https://www.ncbi.nlm.nih.gov/pubmed/26041698
http://dx.doi.org/10.1038/ijo.2015.104