CEA TCB: A novel head-to-tail 2:1 T cell bispecific antibody for treatment of CEA-positive solid tumors

Carcinoembryonic antigen T cell bispecific antibody (CEA TCB) is a bispecific antibody used to recognize CEA and CD3e via a novel molecular format (2:1) that induces T cell-mediated killing of CEA over-expressing tumors while sparing primary cells with low CEA expression. CEA TCB treatment inhibits...

Descripción completa

Detalles Bibliográficos
Autores principales: Bacac, Marina, Klein, Christian, Umana, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007959/
https://www.ncbi.nlm.nih.gov/pubmed/27622073
http://dx.doi.org/10.1080/2162402X.2016.1203498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007959/
https://www.ncbi.nlm.nih.gov/pubmed/27622073
http://dx.doi.org/10.1080/2162402X.2016.1203498

Ejemplares similares