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Retargeting cytokine-induced killer cell activity by CD16 engagement with clinical-grade antibodies

Cytokine-induced Killer (CIK) cells are a heterogeneous population of ex vivo expanded T lymphocytes capable of MHC-unrestricted antitumor activity, which share phenotypic and functional features with both NK and T cells. Preclinical data and initial clinical studies demonstrated their high tolerabi...

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Detalles Bibliográficos
Autores principales: Cappuzzello, Elisa, Tosi, Anna, Zanovello, Paola, Sommaggio, Roberta, Rosato, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007963/
https://www.ncbi.nlm.nih.gov/pubmed/27622068
http://dx.doi.org/10.1080/2162402X.2016.1199311