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Retargeting cytokine-induced killer cell activity by CD16 engagement with clinical-grade antibodies
Cytokine-induced Killer (CIK) cells are a heterogeneous population of ex vivo expanded T lymphocytes capable of MHC-unrestricted antitumor activity, which share phenotypic and functional features with both NK and T cells. Preclinical data and initial clinical studies demonstrated their high tolerabi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007963/ https://www.ncbi.nlm.nih.gov/pubmed/27622068 http://dx.doi.org/10.1080/2162402X.2016.1199311 |