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Distinct mechanisms of B and T lymphocyte accumulation generate tumor-draining lymph node hypertrophy
Tumor-draining lymph nodes (TDLNs) often enlarge in human cancer patients and in murine tumor models, due to lymphocyte accumulation and lymphatic sinus growth. B lymphocytes within TDLNs can drive lymph node hypertrophy in response to tumor growth, however little is known about the mechanisms direc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007965/ https://www.ncbi.nlm.nih.gov/pubmed/27622075 http://dx.doi.org/10.1080/2162402X.2016.1204505 |