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Alterations in nuclear structure promote lupus autoimmunity in a mouse model

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the development of autoantibodies that recognize components of the cell nucleus. The vast majority of lupus research has focused on either the contributions of immune cell dysfunction or the genetics of the disease. Becaus...

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Detalles Bibliográficos
Autores principales: Singh, Namrata, Johnstone, Duncan B., Martin, Kayla A., Tempera, Italo, Kaplan, Mariana J., Denny, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007980/
https://www.ncbi.nlm.nih.gov/pubmed/27483354
http://dx.doi.org/10.1242/dmm.024851