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Alterations in nuclear structure promote lupus autoimmunity in a mouse model
Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the development of autoantibodies that recognize components of the cell nucleus. The vast majority of lupus research has focused on either the contributions of immune cell dysfunction or the genetics of the disease. Becaus...
Autores principales: | Singh, Namrata, Johnstone, Duncan B., Martin, Kayla A., Tempera, Italo, Kaplan, Mariana J., Denny, Michael F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007980/ https://www.ncbi.nlm.nih.gov/pubmed/27483354 http://dx.doi.org/10.1242/dmm.024851 |
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