Model systems of protein-misfolding diseases reveal chaperone modifiers of proteotoxicity

Chaperones and co-chaperones enable protein folding and degradation, safeguarding the proteome against proteotoxic stress. Chaperones display dynamic responses to exogenous and endogenous stressors and thus constitute a key component of the proteostasis network (PN), an intricately regulated network...

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Detalles Bibliográficos
Autores principales: Brehme, Marc, Voisine, Cindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Special Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007983/
https://www.ncbi.nlm.nih.gov/pubmed/27491084
http://dx.doi.org/10.1242/dmm.024703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007983/
https://www.ncbi.nlm.nih.gov/pubmed/27491084
http://dx.doi.org/10.1242/dmm.024703

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